D1 receptor
D2 receptor
D3 receptor
D5 receptor
DAT
D4 receptor

DAT 选择性抑制剂 | 调节剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S6301	MPP+ iodide	MPP+ iodide (N-Methyl-4-Phenylpyridinium Iodide), the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces autophagic cell death in SH-SY5Y cells. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons.	Selective
S3163	Benztropine mesylate	Benztropine(Cogentin mesylate, Benztropine methanesulfonate) is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.	Selective	DAT, IC50: 118 nM